Urapidil Impurity 85 CAS 144965-19-5 (free base)

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.144965-19-5 (free base)
Molecular FormulaC10H16N2O
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Urapidil Impurity 85 CAS 144965-19-5 (free base) chemical structure

Description

CATO supplies Urapidil Impurity 85 (CAS 144965-19-5 (free base)), a pharmacopoeial impurity reference standard (molecular formula C10H16N2OHCl, MW 216.71 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Urapidil Impurity 85 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H16N2O HCl
Molecular Weight216.71 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
Halogen ContentCl-containing
Nitrogen Atoms2

Related Urapidil Standards

Recommended Standards

Why CATO?